Yeah, first of all, no way you're getting true end ( and therefore a lot of the titles ) without a guide, so that's your first problem, just play the game once, then use the perfect ending guide.
Second, I wish I knew how many hours I spent on getting the L.O.X. trophy, I know I spend at least 200 hours just on the synthesizing alone, god. Took AGES. Marie wasn't helping much with the constant failing and giving me grass instead of my high grade items all the time either.
Be prepared for farming a loooot of Hellblaze